Medicinal chemistry is an interdependently established science that
encompasses the innovation, progress, recognition and revelation of the mode of
action of biologically dynamic compounds at the molecular level.
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| Imidazole Derived Schiff Base Analogues |
Heterocycles form by far the most of classical divisions of organic
chemistry and are of vast use in biologically and industrially. Heterocyclic
nucleus imparts an essential function in medicinal chemistry and serves as a
key template for the improvement of various therapeutic agents. Imidazole’s
have in use a sole arrangement in heterocyclic chemistry, and its derivatives
have attracted significant interests in recent years for their multipurpose
properties in chemistry and pharmacology. It improves pharmacokinetic
characteristics of pilot analogues and thus is used as a remedy to optimize
solubility and bioavailability parameters of projected unsuccessfully soluble
lead molecules. The imidazole derivatives possess extensive spectrum of
biological activities such as anti-inflammatory, anti-oxidant, anti-bacterial,
anti-cancer, anti-tubercular and anti-HIV activities etc. Read more>>>>>>>
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