Traditional Medicine Based Drug Development

Currently traditional medicine (TM) is used in primary health care systems in most countries parallel to conventional medicine. Therefore TM should be subjectedto rigorous research for their efficacy and safety for better health care. At present there is a high necessity for evidence based clinical drug development with changing of global economic scene. When developing novel drugs using TM candidates it is essential to consider novel standard parameters whenever possible. Quality control of TM is also prerequisite of standard clinical trials. 

When following evidence based clinical herbal product development cycle it is necessary to follow current standard quality controlling methods viz Good Laboratory Practice (GLP); Good Manufacturing Practice (GMP; Good Clinical Practice (GCP); Chemistry, Manufacturing and Controls (CMC) or PharmaceuticalQuality. World Health Organization (WHO), 2004 has published guidelines for safety issues in herbal product development. According to this categorization it is required to be addressed safety and toxicity before clinical usage of TM.