Friday, 16 June 2017

In Vitro Enhancement of Bacoside in Brahmi (Bacopa monnieri) Using Colchicine

Bacopa monnieri, a small herb, commonly called as Brahmi belongs to the family Scrophulariaceae. It grows in the humid climate, mainly distributed in damp and marshy tracts in the subtropical region of the Indian subcontinent. It requires a well-drained, moist, sandy loam soil, rich in organic matter and grows well at a temperature from 30°C to 40°C. Brahmi is an important Ayurvedic medicinal herb used for the improvement of intelligence, memory and revitalization of sensory organs.

The major chemical entity shown to be responsible for neuropharmacological effects and the nootropic action of B. monnieri is triterpenoid saponin. The medicinal properties of Bacopa monnieri responsible for improving memory related function have been attributed to the presence of different types of saponins such as Bacosides (A, B, C and D) called the “memory chemicals” i.e., important secondary metabolite. (Read more)

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